Molecular analysis of the Coprinus cinereus mating type A factor demonstrates an unexpectedly complex structure.
نویسندگان
چکیده
منابع مشابه
Molecular analysis of the Coprinus cinereus mating type A factor demonstrates an unexpectedly complex structure.
We report here the molecular cloning of the A43 mating type factor from Coprinus cinereus, a basidiomycetous fungus. Our molecular analyses revealed an unexpected source of variation in the A factor. Though genetic studies have demonstrated that A has two subunits, alpha and beta, we located three nonoverlapping fragments in the A43 region that have A factor function following DNA-mediated tran...
متن کاملA large pheromone and receptor gene complex determines multiple B mating type specificities in Coprinus cinereus.
Pheromone signaling plays an essential role in the mating and sexual development of mushroom fungi. Multiallelic genes encoding the peptide pheromones and their cognate 7-transmembrane helix (7-TM) receptors are sequestered in the B mating type locus. Here we describe the isolation of the B6 mating type locus of Coprinus cinereus. DNA sequencing and transformation analysis identified nine genes...
متن کاملThe origin of multiple B mating specificities in Coprinus cinereus.
Mushrooms, such as Coprinus cinereus, possess large families of pheromones and G-protein-coupled receptors that are sequestered at the B mating-type locus and whose function is to confer vast numbers of different mating types. This ability results from complex patterns of cognate and noncognate pheromone/receptor pairings, which potentially offer a unique insight into the molecular interaction ...
متن کاملRecombination and Variation at the A Mating-Type of Coprinus cinereus
The molecular basis of variability at the Coprinus cinereus A mating-type was investigated. The A mating-type controls sexual compatibility in this basidiomycete fungus and, like the S loci of many plants, displays quite high levels of variation in natural populations. The A mating-type is a complex locus made up of a number of genes arranged in gene pairs. We determined the role of recombinati...
متن کاملCorrelation of genetic and physical maps at the A mating-type locus of Coprinus cinereus.
The A mating type locus of Coprinus cinereus is remarkable for its extreme diversity, with over 100 different alleles in natural populations. Classical genetic studies have demonstrated that this hypervariability arises in part from recombination between two subloci of A, alpha and beta, although more recent population genetic data have indicated a third segregating sublocus. In this study, we ...
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ژورنال
عنوان ژورنال: Genetics
سال: 1991
ISSN: 1943-2631
DOI: 10.1093/genetics/128.3.529